HANDBOOK OF EXPERIMENTAL PHARMACOLOGY BY S.K.KULKARNI PDF

Pharm first year second sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course. Pharm R17 first year second sem is as follows. I Year II Sem.

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Pharm first year second sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course. Pharm R17 first year second sem is as follows. I Year II Sem.

Course Objective: This subject is designed to impart the knowledge on preclinical evaluation of drugs and recent experimental techniques in the drug discovery and development.

The subject content helps the student to understand the maintenance of laboratory animals as per the guidelines, basic knowledge ofvarious in-vitro and in-vivo preclinical evaluation processes Course Outcome: Upon completion of the course the student shall be able to, Appraise the regulations and ethical requirement for the usage of experimental animals. Describe the various animals used in the drug discovery process and good laboratory practices in maintenance and handling of experimental animals Describe the various newer screening methods involved in the drug discovery process Appreciate and correlate the preclinical data to humans UNIT I : Laboratory Animals: Common laboratory animals: Description, handling and applications of different species and strains of animals.

Transgenic animals: Production, maintenance and applications Anesthesia and euthanasia of experimental animals. Maintenance and breeding of laboratory animals. Bioassay Principle, scope and limitations and methods UNIT II : Preclinical screening of new substances for the pharmacological activity using in vivo, in vitro, and other possible animal alternative models. General principles of preclinical screening. CNS Pharmacology: behavioral and muscle co ordination, CNS stimulants and depressants, anxiolytics, anti-psychotics, anti epileptics and nootropics.

Drugs for neurodegenerative diseases like Parkinsonism, Alzheimers and multiple sclerosis. Drugs acting on Autonomic Nervous System. UNIT III : Preclinical screening of new substances for the pharmacological activity using in vivo, in vitro, and other possible animal alternative models. Reproductive Pharmacology: Aphrodisiacs and antifertility agents Analgesics, antiinflammatory and antipyretic agents. Gastrointestinal drugs: anti ulcer, anti -emetic, antidiarrheal and laxatives.

UNIT IV : Preclinical screening of new substances for the pharmacological activity using in vivo, in vitro, and other possible animal alternative models. Cardiovascular Pharmacology: antihypertensives, antiarrythmics, antianginal, antiatherosclerotic agents and diuretics. Drugs for metabolic disorders like anti-diabetic, antidyslipidemic agents.

Anti cancer agents. Hepatoprotective screening methods. UNIT V : Preclinical screening of new substances for the pharmacological activity using in vivo, in vitro, and other possible animal alternative models. Immunomodulators, Immunosuppressants and immunostimulants General principles of immunoassay: theoretical basis and optimization of immunoassay, heterogeneous and homogenousimmunoassay systems.

Immunoassay methods evaluation; protocol outline, objectives and preparation. Immunoassay for digoxin and insulin. Limitations of animal experimentation and alternate animal experiments.

Burn D. Finney and I. Goodwin Screening methods in Pharmacology by Robert Turner. Fundamentals of experimental Pharmacology by M. Experimental Pharmacology by R. Preclinical evaluation of new drugs by S. Kulkarni, 3rd Edition.

David R. Screening Methods in Pharmacology, Robert A. Rodents for Pharmacological Experiments, Dr. Tapan Kumar chatterjee. All details and yearly new syllabus will be updated here time to time. Subscribe, like us on facebook and follow us on google plus for all updates. Do share with friends and in case of questions please feel free drop a comment Its Time to try iStudy App for latest syllabus, timetables and updates from JNTUH no ads, no pdfs.

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Handbook of Experimental Pharmacology

Condition: New. Purchasing and Inventory Management have undergone tremendous changes in last few years. New Technologies, new tools, new philosophy and new thinking, Purchasing and Inventory Management has undergone a complete transformation. Though these activities are now viewed as part of the all encompassing Supply Chain Management, Purchasing and Inventory Management are very important and have an independent identity. This book brings out the nuances involved in Purchasing and Inventory Management illustrated with real life examples and cases from Indian companies. The first part of the book deals with Purchasing Management while the second part is on Inventory Management. The two portions are mutually exclusive and can be read together or separately as the reader desires.

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JNTUH M.Pharm 2017-2018 (R17) Detailed Syllabus Pharmacological and Toxicological Screening Methods

Epilepsy describes a condition in which a person has recurrent seizures due to a chronic, underlying process. Epilepsy has been around for more than years and is one of the earliest known maladies. Slide 5: Hippocrates was the first person to dispel the myth of epilepsy, as not being caused by devils and spirits. Hanuptmann : Discovery of Phenobarbital. The classic studies of Meritt and Putamen showed the feasibility of testing of chemical substances for potential clinical antiepileptic benefit by means of a simple electroshock method in cats. Simple a. Absence A.

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