The Dicynone tablet can also cause side effects not mentioned here. If you notice other side effects not mentioned above, contact your doctor for medical advice. You can also report side effects to your local food and drug administration authority. Precautions and How to Use Before using the Dicynone tablet, tell your doctor about your current list of medications, over-the-counter products eg, vitamins, herbal supplements, etc.
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The Dicynone tablet can also cause side effects not mentioned here. If you notice other side effects not mentioned above, contact your doctor for medical advice. You can also report side effects to your local food and drug administration authority.
Precautions and How to Use Before using the Dicynone tablet, tell your doctor about your current list of medications, over-the-counter products eg, vitamins, herbal supplements, etc. Some health conditions may make you more susceptible to the side effects of the medication.
Take as directed by your doctor or follow the address printed on the product leaflet. The dose is based on your condition. Tell your doctor if your condition persists or worsens. Do not use before the onset of bleeding during periods.
Notify your doctor if you are allergic to sulfites or wheat. Pregnant or breastfeeding a baby. Consult your doctor if you have allergic reactions or allergies to sulfonamides or wheat.
Contraindications Hypersensitivity to the Dicynone tablet is a contraindication. The treatment lasts 1. Children: Due to its high concentration of active principle, Dicynone is not appropriate for children. As a precaution, Dicynone should not be administered during the first trimester of pregnancy, while during the second and third trimesters. It should be administered only if the expected therapeutic benefit is considered superior to the potential risk to the fetus.
In the absence of data on the passage to breast milk, breastfeeding is not advisable during treatment or, if breastfeeding should be continued, treatment should be discontinued.
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Active principle: etamsylate Etamsylate mg. E , excipients q. By improving platelet adhesiveness and restoring capillary resistance, it reduces the bleeding time and blood losses. Etamsylate has no. Pharmacokinetics : When given p. After oral administration of mg etamsylate maximum plasma level, i.
Etamsylate - Indications, Dosage, Side Effects and Precautions
It stimulates thrombopoiesis and their release from bone marrow. Haemostatic action is due to activation of thromboplastin formation on damaged sites of small blood vessels and decrease of PgI2 Prostacyclin I2 synthesis; it also facilitates platelet aggregation and adhesion , that at last induce decrease and stop of hemorrhage. It has been shown to reduce bleeding time and blood loss from wounds. This appears to relate to increased platelet aggregation mediated by a thromboxane A2 or prostaglandin F2a dependent mechanism. It has also been associated with decreased concentrations of 6-oxoprostaglandin F1a, a stable metabolite of prostacyclin. Prostacyclin is a potent vasodilator, and may be implicated in reperfusion; it is also a disaggregator of platelets. Whereas prostaglandins themselves may have a role in regulating cerebral blood flow, etamsylate appears to have no effect on cerebral blood flow.
Dicynone 500 tablets Antihemorrhagic